Mastitis: Coliform/Gram-Negative Bacteria Diagnostic Aid

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E. coli and other coliform species, such as Klebsiella, Enterobacter, and Serratia, are gram negative bacteria found in the environment. These gram negative bacteria release endotoxin when they are engulfed by a white blood cell which can cause fever, decreased appetite, weight loss, a decrease in milk production and exacerbate the inflammatory response. Coliform mastitis will lead to inflammation of the mammary glands and damage of the mammary epithelial cells. An increase in vascular permeability in the mammary gland can also result in watery or serous milk.